thiamphenicol

Factory Supply High Quality Thiamphenicol CAS 15318-45-3

Thiamphenicol is a kind of chloromycetin type broad-spectrum antibiotic,its chemical constitution is similar to the chloromycetin's,its armor sulphonebase has substituted for the chloromycetin's niryl,thus the toxicity reduces,its antibacterial function is 2.5-5 times stronger than the chloromycetin.Clinically,the Thiamphenicol mainly uses in intestinal tract surgery,department of obstetrics and gynecology and department of eye;ear;nose and throat for curing the infection,especially has good function to light and moderate infection.Thiamphenicol also has strong immunosuppression action,is one kind of fine immunosuppressant.Its immunosuppression action is much more better than chloromycetin.


Thiamphenicol (also known as thiophenicol and dextrosulphenidol) is an antibiotic. It is the methyl-sulfonyl analogue of chloramphenicol and has a similar spectrum of activity, but is 2.5 to 5 times as potent. Like chloramphenicol, it is insoluble in water, but highly soluble in lipids. It is used in many countries as a veterinary antibiotic, but is available in China and Italy for use in humans. Its main advantage over chloramphenicol is that it has never been associated with aplastic anaemia.Thiamphenicol is also widely used in Brazil, particularly for the treatment of sexually transmitted infections and pelvic inflammatory disease.Unlike chloramphenicol, thiamphenicol is is not readily metabolized in cattle, poultry, sheep, or humans, but is predominantly excreted unchanged. In pigs and rats the drug is excreted both as parent drug and as thiamphenicol glucuronate.