Untargeted Metabolomics

What Is Untargeted Metabolomics?

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untargeted metabolomics service

The LC-MS untargeted metabolomics is used for unbiased detection of metabolites in samples by liquid chromatography-mass spectrometry and to obtain their qualitative and quantitative information. Untargeted metabolomics data analysis, also known as nontargeted metabolomics analysis, entails comparing the metabolomes of control and test groups to pinpoint distinctions in their metabolite profiles that could be pertinent to specific biological conditions.

Technology Introduction
The main application of lcms metabolomics is for comparing the case group with the control group to find the metabolites and metabolic pathways that show significant differences between groups, which can provide clues and directions for the untargeted metabolomics research in biomarker development, disease pathogenesis, and drug treatment mechanisms.

Technical Features of Untargeted Metabolomics Service
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Large Curated Database
Collected ultra-high sensitinity data of over 280,000 metabolites. Each sample can typically identify 1500-3000 metabolites.

Comprehensive Identification Strategy
A comprehensive identification of metabolites was performed using four qualitative methods:

Matching to in-house standard database;

Matching to integrated public database;

Matching to AI database;

Identify using the metDNA algorithm.

Rigorous Quality Control
A mature quality control system monitoring all aspects of experimentation from sample preparetion to data collection.
Why Untargeted Metabolomics Service Is Used?
Genes will tell you what may happen, metabolites tell you what is happening or has happened (Bill Lasley) Metabolomics is the qualitative and quantitative assessment of metabolites (small chemical molecules<1.5 kda). The metabolites are the downstream product of protein activity as well as the result of interactions with environmental exposures, and thus they are closely related to the phenotype. Over the last decade, metabolomics is coming to the forefront as a powerful tool for understanding disease mechanisms. and identifying biomarkers, and has great potential for clinical translation.

As a preeminent metabolomics company with a well-equipped metabolomics laboratory, we provide cutting-edge metabolomics services through scientific metabolomics test and analysis. As a preeminent metabolomics company with a well-equipped metabolomics laboratory, metware library provides cutting-edge metabolomics services through scientific metabolomics test and analysis.