Safe Shipping to EU for Bulk GW501516/Cardarine CAS: 317318-70-0

GW501516 is a well know bodybuilding supplement for bodybuilders, we usually classified GW501516 as SARMs , but GW 501516 does not belong to SAMRs in fact .
Why bodybuilder classified GW 501516 as SARMs ? What the relationship between GW 501516 and SARM ?
We may have many concerns about GW 501516 , let us clarify it one by one .

Why bodybuilder classified GW 501516 as SARMs ?
When we talk about it , we should know GW 501516 benefits ,then we will know something about GW 501516 and SARMs .

GW 501516 Benefits of Increased Endurance
Bodybuilder knows that the use of GW 501516 has great benefit in increasing endurance , can make the bodybuilder adhere to exercise for a longer time , GW 501516 is more suitable for long-distance running , bicycle , weight lifting and other people who need endurance to use . So why GW 501516 benefit for endurance improvement ?
In the study of GW 501516 , the experimental mice were treated with GW 501516 for 3 consecutive weeks , and the exhausted running distance of the experimental mice was greatly increased . Among them , the running distance of the trained mice increased by 744.4 m ( 31.2 % ) , and the running distance of the untrained mice increased by 750.3 m ( 68.6 % ) .
This test shows that GW 501516 has no relationship with whether the mice have been trained or not in improving the running ability of mice . Mice without training at all can increase the running distance by 68.6 % after using GW 501516 .
How does GW 501516 manage to improve endurance ?
This has to do with the way GW 501516 works .
GW 501516 is a selective agonist of the PPARδ receptor -- which actually explains the relationship between GW 501516 and SARMs . GW 501516 is not belong to SARM ( selective androgen receptor agonists ) .
PPAR is a class of ligand-dependent nuclear transcription factors important for metabolic homeostasis . PPARδ is one of three types of PPARs expressed in adipose tissue , liver , skin , brain and skeletal muscle .
PPARδ regulates many different biological activities such as lipid and lipoprotein metabolism , mitochondrial respiration , skeletal muscle reorganization , thermogenesis , inflammation , keratinization , cell differentiation , and wound healing .
Normal bodybuilding is to promote protein catabolism and gluconeogenesis to provide energy needed for bodybuilding , but GW 501516 , as a selective agonist of PPARδ receptor , regulates lipid and protein metabolism . The energy required for bodybuilding is provided by increasing the specific consumption of fatty acids .
The experiment showed that the supplementation of GW 501516 without bodybuilding significantly increased the level of serum unsaturated fatty acids , especially the level of unsaturated fatty acids . When GW 501516 is supplemented with Bodybuilding , the fatty acid level increases even more .
Therefore , GW 501516 does not directly use the energy intake of the body, but regulates the metabolism of lipids in the body to replenish energy , so that the Bodybuilder will not have the feeling of running out of energy , so that it can maintain the bodybuilding for a long time , and is suitable for participating in endurance related physical activities .

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