Nicotinamide

Nicotinamide, also known as nicotinamide, vitamin B3 or vitamin PP, is a water-soluble vitamin, belonging to the B group of vitamins, coenzyme I (nicotinamide adenine dinucleotide, NAD) and Coenzyme II (nicotinamide adenine dinucleotide phosphate, NADP) components, In human body, the niacinamide part of these two coenzyme structures has reversible hydrochemicalbook and dehydrogenation properties, plays a role in hydrogen delivery in biological oxidation, can promote tissue respiration, biological oxidation process and metabolism, and has important significance for maintaining the integrity of normal tissues, especially the skin, digestive tract and nervous system. When lacking, pellagra is caused by the affected respiration and metabolism of cells, so this product is mainly used for the prevention and treatment of pellagra, stomatitis, glossitis and so on.

Nicotinamide is a white acicular crystal or crystalline powder, odorless or slightly smelly, slightly bitter taste. Relative density 1.4, melting point 129-131℃. 1g This product is soluble in 1mL water, 1.5mL ethanol or 10mL glycerin, and insoluble in ether. The PChemicalbookH of 10% aqueous solution is 6.5-7.5. It has weak hygroscopicity. More stable, can resist acid, alkali and high temperature in dry air to light, heat are stable, in alkaline or acidic solution heating to produce niacin. Rat oral LD502.5-3.5g/kg, ADI value is not specified