Mildronate Mildronate Cas 76144-81-5([email protected])

Product details
Name: Mildronate
Synonyms:3-(2,2,2-triMethylhydraziniuM)propionatedehydrate;Mildronate3-(2,2,2-Trimethylhydrazine)propionate;3-(trimethylammonioamino)propionate;3-(trimethylazaniumylamino)propanChemicalbookoate;3-(2,2,2-trimethyldiazan-2-iumyl)propanoatedihydrate;Kvaterin;2-(2-carboxyethyl)-1,1,1-trimethylhydraziniumhydroxideinnersalt;3-(2,2,2-trimethylhydrazine)propionate
CAS NO.:76144-81-5
EINECS: 682-135-0
Molecular formula: C6H14N2O2
Molecular weight: 146.18756
Appearance: White powder
MOQ: 100g
Sample: Available
Storage:Store in cool & dry place, Keep away from strong light and heat.
Purity: 99%
Packaging: 1kg/Aluminum foil bag; 25kg/drum; customized
Payment Terms: Western Union /RIA bank transfer / BTC / TT / Money Gram 
Mode of Transportation: By express or air or sea
Express: Fedex, UPS, DHL. TNT, EMS, EUB, HKEMS
Port: Shanghai, Tianjin,Qingdao, Guangzhou                                                     
Delivery Lead Time: Within 7 days by express, 3-7 days by air, 7- 45 days by sea



Meldonium(also known as THP, MET-88 and mildronate) is a novel cardioprotective agent.

Meldonium acts on mitochondria at the cellular level to improve myocardial energy metabolism. In view of these drugs and other anti-myocardial ischemia significantly different, also known as cell anti-ischemic drugs.
Meldonium is a structural analog of carnitine that competes in the inhibition of butyrate betaine hydroxylase, thereby inhibiting the biosynthesis of carnitine, which directly inhibits the transport of carnitine-dependent fatty acids in mitochondria. Inhibition of carnitine biosynthesis can reduce the concentration of intracellular free carnitine and prevent isoproterenol-induced acyl carnitine accumulation. Therefore, the drug has a significant protective effect on the myocardium, resulting in this protective effect at the same time on the hemodynamic parameters had no significant effect, cardiac blood supply and cardiac oxygen consumption was no significant change.

Function:
1. Meldonium powder is a novel cardioprotective agent.

2.Meldonium acts on mitochondria at the cellular level to improve myocardial energy metabolism. In view of these drugs and other anti-myocardial ischemia significantly different, also known as cell anti-ischemic drugs.

3. Meldonium is a structural analog of carnitine that competes in the inhibition of butyrate betaine hydroxylase, thereby inhibiting the biosynthesis of carnitine, which directly inhibits the transport of carnitine-dependent fatty acids in mitochondria. Inhibition of carnitine biosynthesis can reduce the concentration of intracellular free carnitine and prevent isoproterenol-induced acyl carnitine accumulation.
Therefore, the drug has a significant protective effect on the myocardium, resulting in this protective effect at the same time on the hemodynamic parameters had no significant effect, cardiac blood supply and cardiac oxygen consumption was no significant change.

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