HPMC for Pharmaceutical

HPMC in Pharma
Pharmaceutical grade HPMC Hydroxypropyl methyl cellulose is a widely used pharmaceutical excipient that is used in a variety of applications in the pharmaceutical industry.

Pharmaceutical grade HPMC Hydroxypropyl methyl cellulose is a widely used pharmaceutical excipient that is used in a variety of applications in the pharmaceutical industry.

As an excipient, HPMC is an inactive ingredient that is used to improve the quality, safety, and effectiveness of drug products. Here are some of the main applications of HPMC in the pharmaceutical industry:

Controlled release: HPMC can be used to create controlled-release drug formulations that release the active ingredient at a controlled rate over an extended period of time. This can help to improve the efficacy of the drug and reduce the frequency of dosing.

Tablet coating: HPMC is a common binder used in tablet formulations. It helps to hold the tablet ingredients together, improving the tablet's structural integrity, and ensuring consistent dosage and disintegration.

Film coating: HPMC can be used as a film coating for tablets, vegetable capsules, and granules. It helps to protect the drug from environmental factors and improve its appearance and swallowability.

Disintegrant: HPMC can be used as a disintegrant in tablet formulations to help the tablet dissolve quickly and uniformly in the gastrointestinal tract. This can improve the bioavailability of the drug and enhance its therapeutic effect.

Suspending agent: HPMC can be used as a suspending agent to keep insoluble drug particles in suspension in liquid formulations, such as suspensions and emulsions.

Types of HPMC for Pharmaceutical
HPMC E3
Pharmaceutical excipient grade hydroxypropyl methyl cellulose, also known as hypromellose, is a cellulose-based polymer used in the production of hard capsules, pellet granulation, and film coating.

HPMC E5
KimaCell¬HPMC E5 are of the highest quality and are used in the development and manufacture of formulations.

HPMC E6
KimaCell¬HPMC E6 is soluble in both cold and hot water, is tasteless, odorless, and non-toxic. The production, dose, and quality of hydroxypropyl methylcellulose, a type of cellulose mixed ether, have been rising quickly in China during the past 15 years.

HPMC E15
HPMC E15 is a non-ionic cellulose derivative that can be used as a rheology modifier and thickening agent for aqueous solutions. It provides excellent stability, good film-forming properties, and is heat resistant.

HPMC E50
HPMC E50 is a hydroxypropyl methylcellulose (HPMC) grade with a medium viscosity used as a binder, thickener, and suspending agent in a variety of products.

HPMC E4M
HPMC E4M is a pharmaceutical grade modified cellulose polymer that is used as a binder, disintegrant, stabiliser, and release agent in pharmaceutical formulations. It provides excellent solubility, film forming properties, low-toxicity, and is also used as a suspending agent in oral suspensions.

HPMC F50
HPMC F50 is a hydroxypropyl methylcellulose used as a pharmaceutical binder, disintegrant, and lubricant. It is a white, odorless, tasteless powder that easily dissolves in cold water and has good film-forming properties.

HPMC F4M
HPMC F4M is a cellulose-based excipient used in pharmaceutical and health care products. It is a white to slightly yellowish-white powder, odorless and tasteless.

HPMC K15 LV
HPMC K15 LV is a low viscosity hydroxypropyl methylcellulose (HPMC) used as a suspending and thickening agent in various applications. It is used in pharmaceutical and food products to provide a uniform consistency, increase stability, and improve the product's shelf life.

HPMC K100 LV
HPMC K100 LV is a cellulose ether used as a rheology modifier, suspending agent, and film forming agent. It is a low viscosity grade of Hydroxypropyl Methylcellulose (HPMC) and is suitable for creating solutions of low to medium viscosity.

HPMC K4M
KimaCell¬HPMC K4M hydroxypropyl methyl cellulose provides excellent water retention and solubility, and is an ideal choice for formulating products with a smooth texture and feel.

HPMC K15M
KimaCell¬HPMC K15M is a multi-purpose pharmaceutical excipient, which can be used as a thickener, dispersant, emulsifier and film-forming agent.

HPMC K100M
HPMC K100M is frequently employed as pharmaceutical excipients in the pharmaceutical business as thickeners, dispersants, emulsifiers, and film-forming agents. Moreover, it is utilized for suspensions, ophthalmic preparations, prolonged and controlled release matrix, floating tablets, and film coating and adhesive on tablet medications.

HPMC K200M
For drug-loaded sustained-release systems, KimaCell¬HPMC K200M is employed as the drug skeleton for tablets or the capsule shell.

How To Use HPMC for Pharmaceutical?
HPMC (Hydroxypropyl methylcellulose) can be used to pharmaceutical excipient formulations using different methods depending on the application. Here are some general guidelines for adding HPMC in pharmaceuticals:

01.
Binder: HPMC can be added as a binder to the dry blend of tablet ingredients. The HPMC is typically added to the dry powder blend and mixed thoroughly. Water or another suitable solvent is then added to the blend to form a granulation that is dried and milled to the desired particle size. The resulting granules are then compressed into tablets using a tablet press.

02.
Disintegrant: HPMC can be added as a disintegrant to the dry blend of tablet ingredients. The HPMC is typically added to the dry powder blend and mixed thoroughly. Water or another suitable solvent is then added to the blend to form a granulation that is dried and milled to the desired particle size. The resulting granules are then compressed into tablets using a tablet press.

03
Film coating: HPMC can be added to a coating solution for film-coating tablets. To prepare an HPMC film-coating solution, HPMC is usually dispersed in water or an organic solvent, along with plasticizers and other excipients. The resulting solution is then sprayed onto the surface of the tablet using a spray coating apparatus.

04
Controlled release: HPMC can be added to a drug formulation to create a controlled-release dosage form. The HPMC is typically mixed with the active ingredient and other excipients to form a matrix that releases the drug at a controlled rate over an extended period of time. The matrix can be incorporated into tablets, capsules, or other dosage forms.

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