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SARM AC 262 Synthetic metabolic potency
We know that the metabolites of compounds are defined on the basis of testosterone . Studies have shown that SARM AC 262 is about 66 % metabolically and 27 % androgenically of testosterone . Therefore , we can calculate that the ratio of synthetic metabolism to androgen of SARM AC 262 is 2 .45 : 1 .
The ratio of synthetic metabolites to androgens was about 90 : 1 for RAD 140 and 10 : 1 for LGD 4033 . We can see that the synthetically metabolizable to androgen ratio of SARM AC 262 is not high .
Does this mean that SARM AC 262 is not as effective as other SARMs?
No , because anabolic potency is measured by the androgen effect of the compound itself . When the ratio of testosterone synthesis to androgen is 1 : 1 , measuring a compound at a ratio of 2 : 1 does not mean that the compound is twice as effective as testosterone .
The anabolic potency indicates that the compound has high synthetic metabolism and low androgen . That is , it improves performance with minimal androgen side effects .

The potency of SARM AC 262 is also related to its binding affinity in muscle and bone .
The affinity of SARM AC 262 is Ki 5nm , and the ratio of synthetic metabolites to androgens of Ligandrol is 10 : 1 , but the binding affinity of Ligandrol is Ki 1nm .
This does not mean that SARM AC 262 is more effective than LGD 4033 . LGD4033 is a full agonist of SARM and SARM AC 262 is a partial agonist of SARM . The effect of partial agents is not as dramatic as that of full agonists , but this is not too much of a problem because with mild SARMs such as SARM AC 262 , the dose can be increased depending on the actual bodybuilding condition .
If the full active agent LGD4033 is better , but the partial agonist SARM AC 262 is milder and has fewer side effects .

As a kind of SARM , SARM AC 262 targets androgen receptors in bone and muscle , which is beneficial to bodybuilding while not affecting other organ functions .

How does the SARM AC 262 work?
SARM AC 262 , like any other SARM , induces physical changes by binding to androgen receptors in skeletal muscle , increasing bone strength and muscle growth capacity , and increasing nitrogen retention and strength .
SARM AC 262 targets only skeletal muscle , and it is this selective approach that results in the androgenic activity of this compound being 27% of that of testosterone . The effects of androgens are often seen as oily skin , obesity , gynecomastia and skin acne .
SARM AC 262 is less androgenic than other SARMs , not to mention anabolic steroids .
While SARM AC 262 is not as effective as anabolic steroids , SARM AC 262 May help bodybuilder increase training intensity and bring more value to the effort and time spent by bodybuilder in the gym , helping bodybuilder break the bottleneck , Cross the finish line .

SARM AC 262 benefits
Increases muscle growth and muscle strength
Binding of SARM AC 262 to androgen receptors in muscle tissue , as well as the anabolic potency of SARM AC 262 , promotes muscle growth in bodybuilder .
When bound to androgen receptors in muscle , SARM AC 262 acts as a more potent version of testosterone by increasing the expression of genes responsible for muscle tissue . This effect results in muscle growth beyond what is naturally achievable with a normal bodybuilder . In addition , because SARM AC 262 is highly selective for the androgen receptor to which it binds , it does not leave the user with large amounts of free testosterone and thus does not create the problems seen with anabolic steroids .
The bodybuilder using the SARM AC 262 reports gains of up to 15 pounds of muscle mass over one cycle .
The SARM AC 262 increases muscle strength as well as muscle growth .
The increase in muscle mass leads to the loss of subcutaneous fat , and each pound of muscle added helps burn 150 calories per day . Therefore , using the SARM AC 262 can help reduce some of the extra mass .
Reduces the risk of prostate cancer
Many studies have linked DHT to the development of prostate cancer .
Testosterone is the major circulating androgen , and the major androgen in prostate cells is DHT . Testosterone is converted into DHT by 5-A reductase in prostate cells .DHT has greater affinity for intracellular androgen receptors than testosterone . DHT binds to the AR of prostate cancer cells , activates androgen responsive genes , and plays an important role in the proliferation of prostate cancer cells . Therefore , DHT-AR complex is an essential substance in prostate cells that regulates cell function .
The antagonistic effect of SARM AC 262 on dihydroxy testosterone (DHT) contributes to the reduction of prostate cancer and the risk of prostate cancer .
Treating Alzheimer's disease
SARM AC 262 was developed to treat degenerative cognitive disorders , of which Alzheimer's disease is a cognitive disorder . Initially in animal experiments , Acadia Pharmaceuticals observed that mice with neurodegenerative diseases regained some cognitive function after administration of SARM AC 262 .
SARM AC 262 increases androgen receptor levels and is effective in preventing Alzheimer's disease .
SARM AC 262 can also help enhance spatial memory .
Inhibition of luteinizing hormone
Luteinizing hormone plays a crucial role in sexual development in both men and women . However , if the LH level in the body is too high , it may affect the reproductive system and lead to infertility . Experiments showed that SARM AC 262 could successfully inhibit the long increase of LH level .

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