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Bolandiol
| Price: | US$ 10 / Gram |
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| Minimum Order: | 10 |
| Payment Terms: | Western Union, Money Gram, Bank Transfer, Bitcoin |
| Port of Export: | shenzhen |
Product Details
| Model No.: | 19793-20-5 | Brand Name: | RAWSGEAR |
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| Certification: | ISO9001 |
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| Specification: | Bolandiol is a synthetic anabolic steroid that increases lean body mass and bone mineral density without significantly stimulating the sexual accessory glands of adult male rats. Since bolandiol inhibits the production of gonadotropin and endogenous testosterone (T), we investigated its mechanism of action. We compared the efficacy of boranediol with T,5α-dihydrotestosterone (DHT), 19-nortestosterone (19-NT) and estradiol (E(2)) in vitro and in vivo. Compared with other androgens, Bolandiol has lower affinity for recombinant androgen receptor (AR), and recombinant human progesterone receptor (PR-A, PR-B) and estrogen receptors (ERalpha and β-) 1) has low but measurable affinity. ). |
Packaging & Delivery
| Packaging: | Foil bag and Disguised bag |
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| Delivery/Lead Time: | 3-5 work days |
| Production Capacity: | 1000kg/month |
Product Description
Functional agonist activity is assessed in AR, PR or ER mediated transcription assays. Bolandiol is irritating in all of these assays, but only 4-9% is as effective as T, DHT and 19-NT AR, with 1% efficacy comparable to PR progesterone, 3% and 1% Efficacy was effective with E(2) via ERalpha or ERbeta, respectively. In immature ovariectomized rats, bolandiol is equivalent to T in stimulating the growth of levator ani muscle, but not as effective as T in stimulating accessory gland growth. Bolandiol also stimulated an increase in uterine weight in immature female rats, which was not partially blocked by ICI 182,780, but was not aromatized in vitro by recombinant human aromatase. Simultaneous treatment with the dual 5α-reductase inhibitor dutasteride did not inhibit bolandiol's stimulation of the sex glandular weight compared to T. Since bolandiol exhibits tissue selectivity in vivo, it may act through AR, PR and/or ER.
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Skype: +8615711952876
Whatsapp +8615711952876
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SUPPLIER PROFILE
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| Company: | Wuhan shuiyixi Pharma Chemical LTD | ||
| City/State | wuhan, Hubei | Country: |
China 
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| Business Type: | Export - Manufacturer / Trading Company | Established: | 2017 |
| Member Since: | 2019 | Contact Person | Tina Lin |
SUPPLIER PROFILE
City/State/Country -
wuhan, Hubei
China
Business Type -
Export - Manufacturer / Trading Company
Established -
2017
Member Since -
2019
Contact Person -
Tina Lin