Afoxolaner

Afoxolaner
Afoxolaner for dogs and afoxolaner for cats is used to treat and control flea and tick infestations in dogs and cats. For example, after being ingested by a dog when you apply appropriate afoxolaner dosage for dogs, afoxolaner is distributed throughout the dog's body. When fleas or ticks bite the pet, they are exposed to the drug and killed during their blood meal. Gihi Chemicals also has afoxolaner for cats. Sometimes afoxolaner is used for the treatment of sarcoptic mange or demodectic mange. When afoxolaner is prescribed for the treatment of mange, it is referred to as "extra label" or "off label" use. Inquire us now to get the afoxolaner price.

Afoxolaner Synonym
4-[5-[3-Chloro-5-(trifluoromethyl)phenyl]-4, 5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-oxo-2-[(2, 2, 2-trifluoroethyl)amino]ethyl]-1-naphthalenecarboxamide; Afoxolaner; 1-NaChemicalbookphthalenecarboxamide, 4-[5-[3-chloro-5-(trifluoromethyl)phenyl]-4, 5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-oxo-2-[(2, 2, 2-trifluoroethyl)amino]ethyl]-; Afoxolanerfandachem

Afoxolaner Safety
CAS No.: 1093861-60-9

EC No.: 832-051-7

MF: C26H17ClF9N3O3

MW: 62.587

Parameters of Afoxolaner
Item Specification Results
Appearance White To Off-white Crystalline Powder Complies
Identification HPLC: HPLC Retention Time Confirms To Standard Complies
Melting Point 148-155℃ 148-150℃
Water ≤0.1% 0.07%
Residue Solvents Dichloromethane≤600ppm N.D.
Isopropyl Acetate≤5000ppm N.D.
Isopropanol≤890ppm 2ppm
N, N-Dimethylformamide≤880ppm N.D.
Methanol≤3000ppm N.D.
Tetrahydrofuran≤720ppm N.D.
Triethylamine≤5000ppm N.D.
Residue On Ignition ≤0.1% 0.02%
Related Substances Impurity D≤0.15% N.D.
Impurity F≤0.15% 0.08%
Individual Unknown Impurity≤0.10% 0.06%
Total Impurities≤1.00% 0.38%
Assay(Anhydrous Substance) 98.0%~102.0% 99.10%

Packing:
100g/bag; 500g/bag; 1kg/bag

Recommended storage method:
Store in a cool, dry and ventilated place.

Recommended storage temperature:
2 - 8 ®C

Product usage:
Pharmaceutical intermediates

Benefits of Afoxolaner
Treat and control flea and tick infestations in dogs.
When fleas or ticks bite the dog, they are exposed to the drug and killed during their blood meal.

The treatment of sarcoptic mange or demodectic mange.
When afoxolaner is prescribed for the treatment of mange, it is referred to as 'extra label' or 'off label' use.

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